TB-500 Peptide, Research-Grade Lyophilized Thymosin Beta-4 Analog

TB-500 is a synthetic peptide derived from thymosin beta-4 (Tβ4), a naturally occurring actin-binding protein found in platelets and wound fluid. It is widely studied in preclinical research on cell migration, angiogenesis and tissue repair. Every batch we supply is independently tested, documented and shipped under temperature-controlled conditions, so researchers can rely on consistent material.

For laboratory research use only. Not for human or veterinary consumption. Not a drug, supplement or medical product.

Product Specifications

Specification	Detail
Product name	TB-500 (thymosin beta-4 analog)
Form	Lyophilized (freeze-dried) powder
Available sizes	5 mg / 10 mg
Purity	≥98%
Verification	HPLC and mass spectrometry, batch COA available
Storage (unopened)	2–8 °C, protected from light
Storage (reconstituted)	2–8 °C, do not freeze; follow your lab’s validated stability window
Shipping	Temperature-controlled, tracked

What Is TB-500?

TB-500 is a synthetic peptide related to thymosin beta-4, a 43-amino-acid protein that regulates actin, the structural protein cells use to move and change shape. Because actin dynamics are central to how cells migrate, TB-500 has become a common compound in preclinical studies of wound-healing models.

Mechanisms Explored in Preclinical Research

Published laboratory studies on thymosin beta-4 and its analogs have examined:

Actin regulation: binding G-actin and influencing polymerization, which affects cell motility
Angiogenesis: effects on endothelial cell differentiation and new vessel formation in experimental models
Inflammatory signaling: modulation of cytokine expression in cell and animal models
Cell survival: reduced apoptosis in injury models

Research models have included tendon, ligament, muscle and skin repair. This evidence is preclinical, and nothing here should be read as a claim of safety or efficacy in humans.

Why Researchers Choose Our TB-500

Batch-specific COA with HPLC purity and MS identity data for every lot
Lyophilized format for better stability in transit and storage
Cold-chain handling to protect peptide integrity
Lot traceability from synthesis to shipment
Responsive technical support for research-handling questions

Storage and Handling

Store lyophilized vials at 2–8 °C, away from light and moisture. After reconstitution with a suitable laboratory diluent, keep the solution refrigerated and avoid repeated freeze-thaw cycles. Always follow your institution’s laboratory protocols.

Frequently Asked Questions

Is TB-500 the same as thymosin beta-4?
No. TB-500 is a synthetic analog or fragment related to thymosin beta-4. Check the product COA for the exact sequence and molecular data of each batch.

What purity is your TB-500?
Each batch is tested by HPLC and mass spectrometry, and the COA lists the measured purity. HPLC + MS · > 98%

How should TB-500 be stored?
Keep unopened vials at 2–8 °C, protected from light. Refrigerate after reconstitution.

Is TB-500 approved for human use?
No. TB-500 has no marketing authorization as a medicine and is sold strictly for in-vitro and laboratory research.

Is TB-500 allowed in competitive sport?
No. It is on the WADA Prohibited List. Athletes in regulated sports should not use it.

Legal disclaimer.

Products are sold for laboratory research use only, to qualified researchers. By purchasing, the buyer confirms compliance with all applicable local laws.

actin-related peptide research

TB-500 Peptide